A New York City police officer and three other people were killed in a shooting in Midtown Manhattan on Monday evening, police confirmed at a late-night news conference.

A note found in the gunman's wallet was critical of the NFL and mentioned CTE. The 27-year-old wrote, “Study my brain please. I’m sorry."

Wearing body armor and wielding an assault-style rifle, the alleged gunman burst into a Midtown Manhattan office building shooting victims at random.

Rep. Nicole Malliotakis spoke with Fox News Digital after the deadly shooting that left multiple people including a police officer dead.

Four people were killed, including a police officer, and one was seriously injured when a gunman opened fire inside an office building before killing himself.

Former FBI Special Agent Vito Roselli said one of the biggest challenges with safeguarding city buildings is that many lobbies are open to the public.

A shooting in a Manhattan skyscraper late on Monday that killed four people, including a New York City police officer, has been marked by statements of sorrow and prayers for the victims' families, but no sign of the Republican-controlled U.

At least one police officer and one civilian were shot inside 345 Park Avenue in New York City, according to NBC News. "New Yorkers: there is an active shooter investigation taking place in Midtown right now," New York Mayor Eric Adams wrote on X. The New York Police Department advised people to avoid the area.