Down syndrome affects around one in 640 children born in the US every year, and is the most common genetic cause of intellectual disability. About 15% of Downs cases are due to the presence of an ...

Scientists from Duke-NUS Medical School, working with collaborators at Imperial College London and partners in Europe and the United States, have uncovered new insights into how an additional copy of ...

Researchers found three master genes that alter brain development in Down syndrome, offering new clues about learning and memory differences.

The study links genetic and regulatory changes to increased erythrocyte production and leukemia risk while also identifying oxidative stress as a key factor in these abnormalities. Study: Single-cell ...

Three specific genes on chromosome 21 drive widespread brain changes in Down syndrome, uncovering a new framework for ...

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life. For decades, scientists have ...

Researchers at the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) have uncovered compelling evidence that individuals with Down syndrome experience ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Ashley Brandebura, University of Virginia (THE CONVERSATION) Delivering a ...

As the authors note, Down syndrome offers a rare scientific advantage – because it is caused by a clearly defined genetic change present from conception, researchers can study brain tissue at the very ...