Cytoplasmic dynein is a vital microtubule-based motor protein that drives retrograde intracellular transport, supporting essential cellular functions ranging from organelle positioning to cell ...

Salk Institute and UC San Diego researchers capture first-of-its-kind video of dynein-Lis1 protein interaction, supporting future drug development for neurological disorders LA JOLLA (May 23, ...

A mechanism of dynein-powered metastatic locomotion has been identified using soft tissue models, revealing a new clinical target for breast cancer treatment. New research led by Penn State (PA, USA) ...

The most lethal feature of any cancer is metastasis, the spread of cancer cells throughout the body. New research reveals the mechanics behind how breast cancer cells may invade healthy tissues. The ...

Researchers have uncovered the mechanism by which a protein facilitates the spread of breast cancer cells from the primary tumor into healthy tissue. The discovery not only improves our understanding ...

A human breast cancer cell, adenocarcinoma MDA-MB-231, demonstrates metastatic-like adhesion, spreading and migrating in a collagen matrix designed to mimic soft tissue. New research led by Penn State ...