The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a ...

Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...

Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.

Researchers found microglia influence reproductive hormone signaling through the RANK protein. The discovery links immune cells to puberty control and infertility, and may improve diagnosis and ...

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing ...

Researchers have identified a key role microglia play in the progression of melanoma brain metastases. A research team led by Berta Sanchez-Laorden at the Institute for Neurosciences (Alicante, Spain) ...

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder that causes progressive memory loss and a decline in mental (i.e., cognitive) abilities. Statistics suggest that between 500,000 ...

A Dartmouth study published in Nature Communications reveals that immune cells in the brain use a surprising two-step process to power their search-and-destroy missions. When immune cells rush to ...

Ever since loss-of-function variants in the gene for PILRA, short for paired immunoglobulin-like type 2 receptor alpha, turned up as protecting against Alzheimer’s disease, scientists have wondered ...