Check out our NFL Week 12 picks for the 14 NFL games this week, a week that begins with the Buffalo Bills at Houston Texans on Thursday Night Football on Nov. 20 and ends with the Carolina Panthers at San Francisco 49ers on Monday Night Football on Nov.

KC Joyner's straight-up confidence picks are 43-13 in the last four weeks. See what he thinks will happen this week.

How low can the Kansas City Chiefs go? Eric Edholm assesses the wildly changing NFL landscape in his Week 12 Power Rankings, which feature a brand new team at No. 1.

Now, SportsLine's NFL DFS Optimizer has turned its attention to Sunday's 2025 NFL Week 11 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine. New users can get $50 in Pick6 credits at DraftKings when they play $5.

The Week 10 edition of SI's round table upset picks article cashed in on two different underdog winners. Clare Brennan correctly called the Patriots taking down

Here's who the experts have winning on Sunday afternoon at Nissan Stadium between the Tennessee Titans and Houston Texans for Week 11

Get game prop insights to parlay in this article, including first to score and prop bets for the top players. NFL odds courtesy of BetMGM Sportsbook. Odds updated Wednesday at 1:41 a.m. ET. For a full list of sports betting odds,