NCAA Tournament officially begins Tuesday and Wednesday with First Four action followed by first- and second-round games on Thursday and Friday as part of a rollercoaster opening week that will see the 68-team field quickly shrink to a Sweet 16 in the span of six days.

The field of 68 is set. The annual NCAA men’s basketball tournament is here, with play-in games set for Tuesday and Wednesday and first-round games on Thursday and Friday, at sites across the country.

Here is a complete guide to picking No. 5 Clemson vs. No. 12 McNeese in your 2025 March Madness bracket, including updated odds and our expert predictions for the Midwest Region game.