Gout is a progressive and chronic disease with three stages. Asymptomatic hyperuricemia, which is often discovered through an incidental lab finding, begins the process. This is a relatively long ...

gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric acid ...

Although these lesions are typically a late feature of gout, gouty tophi occasionally present early in the course of disease, either as the initial manifestation of gout or within a few years of first ...

Over the years, gout has grown in clinical complexity. We see many more cases with iatrogenic factors, multiple comorbidities, advanced age and treatment-refractory hyperuricemia and arthritis (Table ...

More than half of patients with gout from the study cohort reported experiencing peripheral neuropathy. A high prevalence of neuropathy exists among patients with gout, with key associations found ...

The diagnosis of gout sets into motion an assessment and therapeutic program for comorbidities, plus an enduring treatment program for gout-flare treatment and prophylaxis and serum urate lowering.

The European Alliance of Associations for Rheumatology - recommends that serum urate should be maintained at <6 mg/dL (360 µmol/L) and <5 mg/dL (300 µmol/L) in those with severe gout. But despite ...

There are four stages of gout, a common and often painful condition affecting joints, most often the big toe. Gout is a form of inflammatory arthritis caused by hyperuricemia. Hyperuricemia is a ...