Type 1 diabetes is characterized by immune-associated destruction of insulin producing pancreatic beta cells resulting in a lifelong reliance on insulin replacement. However, cardiovascular disease ...
Randomized controlled trials may not properly capture ultraprocessed foods’ health effects due to their designs and ...
In the 1940s, medical researchers began using randomized controlled trials to assess the efficacy of health interventions. In RCTs, researchers create randomly assigned treatment and control groups, ...
A landmark Lancet analysis of more than 150,000 trial participants challenges decades of statin side-effect warnings and calls for updated drug labels grounded in randomized evidence. Study: ...
Increased intestinal permeability may underlie frailty in osteoarthritis (OA), yet targeted treatments remain limited. This trial evaluates whether multi-strain probiotics can reduce plasma zonulin ...
A massive review of 23 randomized trials found that statins do not cause the vast majority of side effects listed on their labels. Memory problems, depression, sleep issues, weight gain, and many ...
In this multicenter, open-label, randomized, controlled trial in China, we assigned participants with newly diagnosed Kawasaki disease in a 1:1 ratio to receive prednisolone plus standard treatment or ...
Cardiovascular disease results in around 20 million deaths worldwide and causes around a quarter of all deaths in the UK. Statins are highly effective drugs that lower LDL ("bad") cholesterol levels ...