Nature

Structure-based prediction of T cell receptor recognition of unseen epitopes using TCRen

T cell receptor (TCR) recognition of foreign peptides presented by major histocompatibility complex protein is a major event in triggering the adaptive immune response to pathogens or cancer. The ...
Nature

Can AlphaFold’s breakthrough in protein structure help decode the fundamental principles of adaptive cellular immunity?

T cells are a key pillar of our adaptive immune response against foreign pathogens and hold an essential role in disease surveillance. These cells are often classified into two canonical classes, ...
Business Wire

Eureka Therapeutics Announces Publication of Crystal Structure of TCR Mimic Redirected T Cells Targeting Alpha-Fetoprotein (AFP) for Liver Cancer

EMERYVILLE, Calif.--(BUSINESS WIRE)--Eureka Therapeutics, Inc., a clinical-stage biotechnology company developing novel T cell therapies to treat solid tumors, today announced the publication of a ...
Fred Hutch

Tinkering with T cells

“There’s 40 million T cells in this little thing,” graduate student Alex Salter said as he held up a tightly sealed, plastic flask about the size and shape of a pocket paperback. The liquid inside ...