DNA polymerase theta (Pol θ) orchestrates a distinct, error-prone route of double-strand break (DSB) repair known as microhomology-mediated end joining (MMEJ) or theta-mediated end joining (TMEJ).
DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...
In eukaryotic cells, DNA replication is organised both spatially and temporally, as evidenced by the stage-specific spatial distribution of replication foci in the nucleus. Despite the genetic ...
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