Its Wednesday, May 21 and the Royals (27-23) are in San Francisco to take on the Giants (29-20). Daniel Lynch is slated to take the mound for Kansas City against Logan Webb for San Francisco.

Preview the May 20 matchup between the San Francisco Giants and Kansas City Royals with odds over/under, game spread, betting lines and more.

The Giants really needed that elite Webb in the rubber match against the Royals ahead of a nine-game, three-city road trip. If his newfound strikeout prowess wasn’t going to show up, his ability to induce weak contact and work late into games would work.

Salvador Perez belted a two-run home run, Maikel Garcia and Bobby Witt Jr. also drove in a pair of runs and the Kansas City Royals completed a road-series win over the San Francisco Giants with an 8-4 romp on Wednesday afternoon.

The Royals waited until the last moment to divulge their pitching plans for Wednesday’s series finale against the Giants at Oracle Park. They had plenty of options available to them. They brought Triple-A prospect Luinder Avila along on the taxi squad in case of an emergency — he was stretched out and could’ve started, if needed.

MLB player prop bets and odds for Heliot Lemuel Ramos on Wednesday, May 21, 2025, as the San Francisco Giants take on the Kansas City Royals.

The Minnesota Twins will try to start another home winning streak when they play the Kansas City Royals on Friday night to open a three-game series in Minneapolis.

Kris Bubic threw seven scoreless innings, losing a no-hit bid in the sixth on an official scoring change, and Vinnie Pasquantino hit a two-run homer in the eighth as the Kansas City Royals got past the San Francisco Giants 3-1.