San Francisco 49ers running back Christian McCaffrey explained why he sometimes feels uneasy sleeping in a hotel room amid ...

Christian McCaffrey credited his wife, Olivia Culpo, for taking care of their newborn daughter while he's at San Francisco ...

The 49ers saw top draft pick Mykel Williams exit with a hyperextended knee in their spirited joint practice with the Denver ...

Christian McCaffrey shared he feels dad guilt leaving Olivia Culpo home with baby Colette as he trains for the NFL season ...

Since quarterback Brock Purdy took over as the 49ers' starting quarterback midway through the 2022 season, the team's offense ...

Evaluating the risk-factors of Christian McCaffrey and his ability to be drafted in the first round of your fantasy football ...

San Francisco 49ers running back Christian McCaffrey joins NFL Network's David Carr and NFL Network Insider Mike Garafolo on ...

The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

The San Francisco 49ers could use more capable running backs on their roster and signing Jeff Wilson Jr. gives them another.

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...