Genetic deficiency of otoferlin, a protein critical to synaptic transmission by the sensory hair cells of the ear, causes congenital deafness. Medicines to treat the condition are lacking; children ...

Objectives: Electrocochleography (ECOG) is a composite objective measure of the cochlea and the cochlear nerve responses. The objectives of this study were to investigate the evolution of ECOG after ...

He was pivotal in discovering how sound waves are converted into signals that the brain can perceive as a whisper, a symphony or a thunderclap. By Jeré Longman Dr. A. James Hudspeth, a neuroscientist ...

The tectorial membrane (TM) is a critical component in the auditory system, playing a pivotal role in stimulating hair cells and facilitating sound transmission. Abnormalities in the TM are commonly ...

Although cell therapy was first performed in 1958 when French oncologist Georges Mathe transplanted bone marrow stem cells after six nuclear researchers were accidentally exposed to radiation, ...

Abstract: Objective: Neural health refers to the condition and functionality of the auditory nerve fibers (ANFs), essential for transmitting sound signals from the cochlea to the brain. However, ...

Intra-arterial Paraplatin did not cause hearing loss in children with retinoblastoma, as shown by DPOAE testing. DPOAE testing is a noninvasive, reliable method for assessing cochlear function and ...

Most cochlear nerves carry information from the cochlea to the brain, but about 5% send signals in the opposite direction: from the brain to the cochlea. The exact role of those fibers has been a ...

The brain may play a role in helping the ear regulate its sensitivity to sound and compensate for hearing loss by sending a signal to a structure in the inner ear known as the cochlea, according to a ...

Uniquely among our sensory organs, the ear expends energy to amplify the very stimuli that it detects. This “active process” endows the cochlea with exceptional sensitivity, sharp frequency tuning, ...