Dysfunctional Family. A family tree of tau folds now incorporates two new structures—P301L, P301T (bottom)—and fills in ...

Having a better midlife diet associated with better functional connectivity between the hippocampus and both the occipital ...

This new cryo-EM structure represents a remarkable advance in our understanding of how human PINK1 is stabilized” said ...

In other words, every successive birth cohort has a lower risk of dementia than did its predecessor. Extrapolated forward, these rates would predict only a 25 percent bump in dementia cases by 2050.

For years, the Alzheimer’s disease field has been on a quest for the perfect blood marker. Such a test could spare patients from invasive lumbar punctures, broaden care access, and allow AD cases to ...

Their clinical AD data analysis began with a GWAS on a clinical AD cohort in which nearly half of participants had non-European ancestry, the dataset from the National Institute on Aging Genetics of ...

Trust Your Intuition? Starting with 126,640 people who downloaded the Intuition study app, recruits went through consent, eligibility screening, study orientation, and an initial CANTAB assessment, ...

Plaques all but vanish in response to some Aβ immunotherapies. Scientists suspect microglia orchestrate the mop-up, but don’t know how, exactly. Now, David Gate of Northwestern University in Chicago ...

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